Overview Features Specifications Resources
PIPETMAN® M96

Accelerate Plate Workflows Without Sacrificing Precision

Science moves fast, and your time at the bench is valuable. PIPETMAN® M96 is a convenient and intuitive electronic pipette designed for high-throughput pipetting on 96- and 384-well microplates. With advanced ergonomics, a guided touchscreen, and optimized accessories to maximize bench space, it turns repetitive pipetting into a process that feels natural, seamless, and reliable. Core features include:

  • 96-channel pipetting for rapid plate filling and reagent distribution
  • Intuitive touchscreen interface with guided protocol steps
  • Ergonomic design to reduce fatigue during repetitive workflows
  • Compatibility with PIPETMAN DIAMOND Tips; no specialty tips, no additional cost
  • SLAS-compatible microplate support for seamless integration with standard labware

Product Features

PIPETMAN® M96

Designed for Efficient Plate Handling

High-throughput workflows demand both speed and consistency. PIPETMAN® M96 helps you fill, transfer, or mix across an entire microplate in seconds while maintaining the accuracy and reliability expected from Gilson pipetting systems. By reducing variability from repetitive tasks, it supports consistent, reproducible results at high throughput.

Designed for scientists working with 96- and 384-well plates, PIPETMAN M96 reduces hands-on time from repetitive plate pipetting in applications such as ELISA, PCR/qPCR preparation, cell culture, and drug screening.

Its intuitive touchscreen interface and ergonomic design help streamline complex plate workflows while reducing repetitive strain during long days at the bench. Compatible with trusted PIPETMAN DIAMOND Tips and SLAS-standard labware, PIPETMAN M96 integrates easily into existing workflows without requiring proprietary consumables.

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Choose the Right Volume for Your Workflow

From low-volume precision to higher-volume reagent handling, PIPETMAN M96 models are designed to match your application needs while maintaining consistent performance across every well.

Accessories Image

Enhance your workflow with accessories designed to support efficient plate handling and organized workspaces. PIPETMAN® M96 accessories work seamlessly with SLAS-standard microplates, helping you stay organized without taking up extra bench space

Consumables Image

No need for specialty tips! PIPETMAN® M96 is designed for use with standard PIPETMAN® DIAMOND Tips, ensuring reliable sealing and consistent liquid handling performance across all channels. Using the same trusted tips across Gilson manual pipettes and plate-based systems also helps simplify laboratory inventory and maintain consistent results.

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Software Image

With PIPETMAN M96 Software, you can create, save, and transfer protocols directly on a computer, providing an alternative to designing protocols through PIPETMAN M96’s built-in Custom Mode. Additionally, it offers access to firmware updates that help maintain optimal performance.

PIPETMAN® M96: Everything You Need to Know About the 96-Channel Electronic Pipette

PIPETMAN M96 is a compact, high-performance 96-channel electronic pipette designed to simplify and accelerate plate-based laboratory workflows. Combining automation-level efficiency with the flexibility of a benchtop instrument, it enables simultaneous pipetting across 96 wells while remaining compatible with standard PIPETMAN® DIAMOND tips and SLAS labware. Ideal for applications such as PCR setup, ELISA, serial dilutions, and plate replication, PIPETMAN M96 helps laboratories increase throughput, improve consistency, and reduce hands-on time, without the complexity or cost of fully automated systems.

Yes. PIPETMAN M96 is fully compatible with standard SLAS-format microplates, ensuring seamless integration into existing lab workflows.

It works with:

  • 96-well microplates
  • 384-well microplates
  • Standard SLAS labware
  • 0.2 mL tubes (with optional rack: 96x0.2 mL, for PCR tubes, strips & PCR plates diam. 7.8mm)

No proprietary plates are required, allowing full flexibility and easier procurement.

Yes. PIPETMAN M96 enables pipetting in 384-well microplates in just four movements using its 96-channel head.

With the Reversible Tray (96/384):

The plate is manually slid from one corner of the tray to the next:

  1. Align tips with the first quadrant → Pipette
  2. Slide to the second quadrant → Pipette
  3. Slide to the third quadrant → Pipette
  4. Slide to the fourth quadrant → Pipette

In four simple steps, the entire 384-well plate is filled.

With the Multi-Tray:

The multi-tray offers guided movement using:

  • A back-and-forth lever
  • A lateral sliding lever (free slide or notched positions)
  • A 384-position setting

Each shift positions the next series of wells under the tips, allowing full 384-well coverage with precision and control.

Result: Efficient 384-well pipetting without the need for a dedicated 384-channel instrument.

Three rotating tray models are available to adapt to different workflows.

All trays:

  • Are reversible, can fit both 96 and 386 wells plate
  • Can be installed on the left or right side
  • Remain stable during pipetting thanks to a magnetic fixing system
  • Can be stacked to save space

Single Reversible Trays (96- / 384-Well)

The single tray and rotating tray adapted to 384-well microplates enable you to slide the microplate manually from one corner to another and fill a 384-well plate with 96 tips.

  • Rotating reversible tray 96-well left side – 384-well right side
  • Rotating reversible tray 384-384 well sides

Ideal for laboratories transitioning between plate formats.

Multi-Tray for 96- and 384-Well Microplates

The multi-tray is equipped with two shifting levers: one to move back and forth the 384-well microplate, and one to set the preferred option to move the tray sideways - free sliding or with notches. It is designed for:

  • Serial dilutions
  • Plate-to-plate transfers
  • Sliding between plates during workflows

No, PIPETMAN M96 uses standard PIPETMAN® DIAMOND Tips.

This means:

  • No hidden long-term consumable costs
  • No dependency on specialty tips
  • Easy integration into labs already using PIPETMAN consumables

Using standard, widely available tips help laboratories control operating costs over time.

PIPETMAN M96 is designed for intuitive operation. It features:

  • A fully integrated touchscreen interface
  • Assisted, step-by-step workflow guidance
  • Clear visibility of upcoming protocol steps

During protocol execution, the next steps are displayed in real time, helping reduce surprises and minimize user error. Users can also program, store, and run customized workflows with confidence.

PIPETMAN M96 includes an Admin control function that supports compliance with most Standard Operating Procedures (SOPs).

  • Protocols and parameters can be locked
  • Access can be controlled via PIN code
  • Custom workflows can be protected

PIPETMAN M96 is compact and space efficient.

Dimensions (W × L × H): 340 × 210 × 450 mm Weight: Approx. 10.2 kg (without accessories)

  • Fits easily on standard benches
  • Can be used under fume hoods and laminar flow hoods
  • Allows microplates to be stacked underneath the pipetting head to save space

Yes. PIPETMAN M96 is fully transportable.

  1. Align and lock the pipetting head using the locking bar.
  2. Carry using the transport handle while supporting the base.
  3. Unlock before resuming pipetting.

This portability makes it ideal for multi-room or shared lab environments.

Power Supply:

  • Voltage: 90–264V AC
  • Frequency: 47 to 63 Hz
  • Output: 24V DC, 3.75A (90W)

Environmental Conditions:

  • Degree of pollution: indoor use level 2
  • Operating temperature: 5°C to 40°C
  • Max humidity: 80%
  • Altitude: up to 2000 m

Storage Conditions:

  • Temperature: -20°C to 50°C
  • Max humidity: 80%
  • Housing: Polystyrene (PS)
  • Pin Plate: Polyoxymethylene (POM) and Stainless Steel
  • Structural components (arm, base, trays): Aluminum

These materials provide durability while maintaining manageable weight.

All models can be connected to PIPETMAN M96 software to create custom protocols on a computer and upgrade the firmware version with a wire. PIPETMAN M96 Bluetooth-connected models are available in select locations. Please contact your Gilson representative for more details.

PIPETMAN M96 is designed to accelerate plate-based workflows across research, biotech, and regulated laboratories.

Key Applications

  • PCR / qPCR – Plate replication
  • ELISA – Plate reformatting and reagent addition
  • Cell culture – Media and reagent addition
  • Drug compound screening – Compound transfer
  • Crystallography – Micro solid-phase extraction (µSPE)
  • Plate-to-plate transfers – 96- and 384-well formats

In ELISA protocols, PIPETMAN M96 significantly reduces hands-on time while improving consistency.

It is particularly effective for:

  • Plate reformatting
  • Reagent addition
  • Serial dilutions
  • Plate replication
  • Addition of stop solution

By pipetting 96 wells simultaneously, laboratories can streamline microplate filling and reduce variability linked to human factors. Studies and workflow evaluations show substantial time savings compared to manual single channel or multichannel pipettes, especially in high-throughput ELISA testing environments.

This makes it ideal for labs looking to increase throughput without investing in large automated platforms.

Typical PIPETMAN M96 users operate in:

  • Pharma
  • Biopharma
  • Biotech
  • Diagnostic laboratories
  • CROs (Clinical Research Organizations)
  • MROs (Medical Research Organizations)
  • Academic institutions
  • Food, cosmetics, chemistry, environmental, and forensic labs

It is particularly attractive for:

  • High-throughput labs processing large numbers of microplates
  • Laboratories aiming to improve efficiency without full automation
  • Academic labs with budget constraints seeking productivity gains
  • Facilities wanting to reallocate technician time to higher-value tasks

PIPETMAN M96 offers multiple pipetting modes to support diverse workflows:

Standard Pipette: For routine applications, including partial plate filling with partial tip fitting.

Reverse Mode for:

  • Dense or viscous liquids
  • Foaming solutions
  • High vapor pressure liquids
  • Cold or hot samples

Mix

  • Mixing immediately after dispensing
  • Multiple mix cycles for tip pre-wetting at mid or low speed (recommended for accuracy)

Repetitive

  • Dispensing aliquots
  • Filling multiple plates
  • Reagent addition and plate preparation Serial Dilution
  • Pipette any volume (within the range of the instrument) from one column (8 tips) to the next in the plate, same volume will be aspirated and dispensed in all columns.
  • Mix automatically after each dispensing and move forward repeating from step 1

Plate-to-Plate

  • Plate replication
  • Plate reformatting
  • Transfers using one to four different liquids
  • Compatible with 96- and 384-well source and destination plates

Manual Mode

  • Supernatant removal
  • Multiple dispenses without preset volumes
  • Titrations
  • ELISA stop-solution addition

Custom Mode

  • Personalized protocols
  • X-fold serial dilutions
  • Partial plate filling
  • Multi-liquid workflows

With its wide range of pipetting modes and application flexibility, PIPETMAN M96 adapts to evolving workflows while maintaining consistency, speed, and control - bridging the gap between manual pipettes and fully automated systems.

PIPETMAN M96 and its accessories are designed so that the parts in contact with contaminants can regularly and easily be cleaned and decontaminated. Standard laboratory cleaning and disinfecting solutions can be wiped on the pipette, such as sodium hypochlorite (chlorine bleach), hydrogen peroxide, ethanol, and surface decontaminants (eg. RNaseZap, Lookout® DNA Erase).

Specifications

SKUGFAM00143
RangePIPETMAN M96
ModelPIPETMAN M96
Adjustable or Fixed VolumeAdjustable Volume
Pipette Tips Included2 x PIPETMAN® DIAMOND Tips Blister Refill 384-certified DS200 autoclavable
Number of Channels96
Amperage90-264V AC
CalibratedYes
Frequency47 to 63 Hz
ProgrammabilityYes
SoftwarePIPETMAN M Connected Software
DisposableReusable
MaterialHousing: Polystyrene (PS), Pin Plate: Polyoxymethylene (POM), Stainless Steel, Metal parts: Aluminum
Product Dimensions (L x W x H)34 x 21 x 45 cm
Product Length (Metric)34 cm
Product Weight (Metric)10.2 kg
Product Weight (Imperial)22.49 lb
Warranty2 years

Service & Calibration

Maintaining pipette accuracy is essential for reliable, reproducible results. Gilson offers professional calibration, preventive maintenance, and repair services performed by factory-trained technicians following rigorous quality standards. Regular service helps ensure your tools continue to deliver accurate performance while minimizing downtime and extending the lifespan of your instrument.

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Application & Technical Support

Gilson specialists are available to support your workflows from installation through daily use. Our team of application scientists and technical experts can help optimize protocols, answer technical questions, and ensure your lab tools perform reliably within your workflows, helping you maintain consistent results and confidence in your data.

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Resources

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Whether you need product advise, have a technical question or need help with your account, our experts are here to assist you every step of the way.