Gilson Connect
This application note demonstrates the use of EXTRACTMAX™ for fully automated magnetic bead–based purification of proteins, with a focus on preserving weak and transient protein–protein interactions. Using Gilson’s exclusion-based sample preparation (ESP™) technology, EXTRACTMAX gently transfers magnetic beads through multiple wash steps without centrifugation or harsh aspiration. The study highlights reproducible protein recovery, minimal sample loss, and parallel processing of up to four samples, illustrating how EXTRACTMAX supports reliable and automated magnetic purification workflows.
ELISA protocols rely on precise, repetitive pipetting steps that can quickly become time-consuming. This article explores how PIPETMAN® M96 enables simultaneous 96-well dispensing to streamline plate preparation, reduce variability, and cut pipetting time by up to 70%.
Processing thousands of wildlife samples for next-generation sequencing can overwhelm manual workflows. This case study shows how the Peery Wildlife Ecology and Conservation Lab automated key NGS steps with PIPETMAX® 268, reducing errors, doubling throughput, and enabling their team to scale conservation genomics research more efficiently.
Automation doesn’t have to mean overhauling your entire workflow. This article explores how task-based automation helps laboratories automate specific steps, like plate setup, normalization, or sample preparation, to improve consistency, reduce errors, and scale workflows such as qPCR, NGS, and ELISA more efficiently.
To validate a novel, non-targeted diagnostic method for preeclampsia, researchers at UTCBS needed to process 263 clinical samples across 16,000+ wells. With PIPETMAX® 268, they successfully automated their liquid handling workflow, improving throughput, conserving sample volume, and enabling the statistical reproducibility necessary for meaningful machine learning analysis.
This application note outlines the automation of the Agencourt® AMPure® XP PCR purification system using Gilson’s PIPETMAX® 268. Designed to streamline PCR cleanup for next-generation sequencing workflows, the protocol uses SPRI magnetic beads to remove contaminants and isolate DNA fragments over 100 bp. The automated method improves reproducibility and throughput, processing up to 96 samples per run with a customizable magnetic bead separator. Applied to E. coli K12 gDNA libraries, the system produced high-quality fragments between 700–2000 bp with no contamination. The protocol is flexible, allowing users to adjust variables like reagent volumes, incubation times, and wash steps to fit diverse lab needs.
Normalization Assistant simplifies the creation of automated normalization protocols without the need for programming. Designed to support flexible workflows, it enables users to import and export sample data, perform QC checks, and configure normalization patterns tailored to a wide range of experiments. With intuitive setup and auto-generated protocols, it reduces manual entry errors and enhances reproducibility, allowing researchers to focus on their science and accelerate their results.
Discover how qPCR Assistant, paired with PIPETMAX® 268 and PIPETMAX® 278, simplifies automated qPCR setup for tens or hundreds of samples, with no programming required. Create singleplex or multiplex protocols, manage sample data with ease, and eliminate manual entry errors. With optimized plate setup, flexible automation, and support for various qPCR cyclers, this intuitive tool boosts reproducibility, traceability, and efficiency in your lab. Learn how to build and run your own workflows in minutes.
Quantitative PCR (qPCR) is a cornerstone of molecular biology, used for applications ranging from gene expression analysis to pathogen detection. However, accurate qPCR results depend on precise liquid handling, making pipetting a critical yet time-consuming step.
Quantitative PCR (qPCR) is essential for gene expression analysis and pathogen identification in life science labs. While qPCR is sensitive, its plate preparation is time-consuming and requires skilled technicians. Automation enhances efficiency and reproducibility. This study compared manual pipettes, the semi-automated TRACKMAN® Connected, and the fully automated PIPETMAX® 268 liquid handler. All tools provided precise results with varying degrees of automation. Choose manual, semi-automated, or fully automated solutions to optimize processes, improve traceability, reduce errors, and free up time for critical tasks.
