Using Liquid Level Detection to Measure Partition Coefficients of Vanillin in Biphasic Solutions

Sample preparation for any form of analysis can be tedious and time-consuming, and efforts to automate this process have been long and fruitful. Today, many different types of liquid handlers exist that can perform a variety of functions to increase throughput tremendously. In this application note, we demonstrate one example of sample prep by taking a common but complicated screening method for optimizing liquid-liquid chromatography run parameters and automating the process. We also showcase the use of liquid level detection in the precise liquid handling of biphasic solutions.